In this study, we consider residual-based bootstrap methods to construct the confidence interval for structural impulse response functions in factor-augmented vector autoregressions. In particular, we compare the bootstrap with factor estimation (Procedure A) with the bootstrap without factor estimation (Procedure B). Both procedures are asymptotically valid under the condition , where N and T are the cross-sectional dimension and the time dimension, respectively. However, Procedure A is also valid even when with 0 ≤ c < ∞ because it accounts for the effect of the factor estimation errors on the impulse response function estimator. Our simulation results suggest that Procedure A achieves more accurate coverage rates than those of Procedure B, especially when N is much smaller than T. In the monetary policy analysis of Bernanke et al. (Quarterly Journal of Economics, 2005, 120(1), 387-422), the proposed methods can produce statistically different results.